Yuh Min Chook ’88: Exploring the Gateway to the Cell Nucleus
Posted November 13, 2009
Biophysicist Yuh Min Chook ’88 studies the mechanisms of protein transport through the nuclear membrane by transporter proteins, or Karyopherin betas (Kap betas), and their traffic patterns. In 2006, Chook’s lab discovered a new signal by which Kap betas identify their cargoes. This year, her lab identified the structure of the export-Kap beta that transports the majority of proteins from the nucleus into the cytoplasm, including proteins that are involved in human diseases such as cancer, AIDS, and cardiac hypertrophy … Read more»